From fish to frogs and beyond: Impact and host range of emergent ranaviruses
Loading...
Authors
Price, Stephen J.
Ariel, Ellen
Maclaine, Alicia
Rosa, Goncalo M.
Grey, Matthew J.
Brunner, Jesse L.
Garner, Trenton W. J.
Issue Date
2017
Type
Article
Language
Keywords
Disease , Host range , Ranavirus , emerging pathogen
Alternative Title
Abstract
Ranaviruses are pathogens of ectothermic vertebrates, including amphibians. We reviewed patterns of host range and virulence of ranaviruses in the context of virus genotype and postulate that patterns reflect significant variation in the historical and current host range of three groups of Ranavirus: FV3-like, CMTV-like and ATV like ranaviruses. Our synthesis supports previous hypotheses about host range and jumps: FV3s are amphibian specialists, while ATVs are predominantly fish specialists that switched once to caudate amphibians. The most recent common ancestor of CMTV-like ranaviruses and FV3-like forms appears to have infected amphibians but CMTV-like ranaviruses may circulate in both amphibian and fish communities independently. While these hypotheses are speculative, we hope that ongoing efforts to describe ranavirus genetics, increased surveillance of host species and targeted experimental assays of susceptibility to infection and/or disease will facilitate better tests of the importance of hypothetical evolutionary drivers of ranavirus virulence and host range.
Description
Citation
Price, S. J., Ariel, E., Maclaine, A., Rosa, G. M., Gray, M. J., Brunner, J. L., & Garner, T. W. J. (2017). From fish to frogs and beyond: Impact and host range of emergent ranaviruses. Virology, 511, 272�"279. doi:10.1016/j.virol.2017.08.001
Publisher
License
Creative Commons Attribution 4.0 International
Journal
Volume
Issue
PubMed ID
ISSN
0042-6822