Prognostic impact of diabetes mellitus on hepatocellular carcinoma: Special emphasis from the BCLC perspective
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Authors
Su, Yu-Wen
Liu, Po-Hong
Hsu, Chia-Yang
Lee, Yun-Hsuan
Hsia, Cheng-Yuan
Ho, Shu-Yein
Hou, Ming-Chih
Chen, Harn-Shen
Huo, Teh-Ia
Issue Date
2017
Type
Article
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Abstract
Background Diabetes mellitus (DM) is associated with higher incidence and poorer prognosis of hepatocellular carcinoma (HCC). The influence of DM on patient survival in different HCC stages is not known. Methods A prospective dataset of 3,182 HCC patients was collected between 2002 and 2014. Patients were divided into three groups according to BCLC stages (BCLC stage 0 and stage A, BCLC stage B, BCLC stage C and stage D). We compared the cumulative survival rate of diabetic and non-diabetic patients in different BCLC groups. The correlation between DM and overall survival was also analyzed by multivariate Cox regression model within each group. Results
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Citation
Su, Y.-W., Liu, P.-H., Hsu, C.-Y., Lee, Y.-H., Hsia, C.-Y., Ho, S.-Y., … Huo, T.-I. (2017). Prognostic impact of diabetes mellitus on hepatocellular carcinoma: Special emphasis from the BCLC perspective. PLOS ONE, 12(3), e0174333. doi:10.1371/journal.pone.0174333
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Creative Commons Attribution 4.0 International
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ISSN
1932-6203