Insights into Clathrin-Independent Endocytotic Pathways of Cholera Toxin
Loading...
Authors
Bogert, Juliana N.
Issue Date
2018
Type
Thesis
Language
en_US
Keywords
Alternative Title
Abstract
The following literature review aims to provide a comprehensive overview of the pathogenic bacteria Vibrio cholerae and its manifestation as a gastrointestinal disease. Chapter 1 will discuss the pathophysiological method of colonization and infection, diagnostic process, clinical features of the disease, and treatment plans for patients infected with cholera. Additionally, we will discuss environmental factors and epidemiology of the disease, as well as prevention methods and problems going forward in cholera research. Chapter 2 will focus on two experiments that shed light on understanding the mechanisms by which cholera toxin (CT) is endocytosed into host epithelial cells is critical for understanding the pathogenesis of Vibrio cholerae and thus for the development of treatment and prevention against cholera. While clathrin-dependent mechanisms of endocytosis have been well-understood, clathrin-independent mechanisms have been less studied.
Description
The University of Nevada, Reno Libraries will promptly respond to removal requests related to content that violates intellectual property laws, data protections, or has been uploaded without creator consent. Takedown notices should be directed to our ScholarWolf team (scholarwolf@library.unr.edu) with information about the object, including its full URL and the nature of your complaint.
Citation
Publisher
License
In Copyright